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RESEARCH SCIENTIST/ENGINEER 3

University of Washington
Seattle, WA Full-time
Posted on August 30, 2019
Req #: 170279
Department: ANESTHESIOLOGY & PAIN MEDICINE
Job Location: South Lake Union
Posting Date: 07/30/2019 
Closing Info: Open Until Filled 
Salary: Salary and benefits are competitive. Salary is commensurate with qualifications and experience. 
Shift: First Shift 
Notes: As a UW employee, you will enjoy generous benefits and work/life programs. 
For detailed information on Benefits for this position, click here.
 

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a “Great College to Work For” for five consecutive years.

The Northwest Metabolomics Research Center (NW- MRC) laboratory utilizes and develops the latest technological advancements in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) methods for analyzing biological samples from a variety of bio-samples. The emerging area of metabolomics describes the simultaneous detection and quantitative measurement of large numbers of metabolites in biological samples such as normal and pathological tissue and bio-fluids. Detection of multiple metabolites, which are the end products of a multitude of genomic and proteomic functions promise immense applications in early diagnosis, prognosis and molecular level understanding of metabolic pathways associated with many diseases.  In addition, the lab is involved in the development of new chemical and technical methods for the enhancement of sensitive and selective biomarkers in various cancers and other diseases.

The NW-MRC’s goals are threefold:                                                                                                                                        
1. Develop and perform cutting-edge research in metabolite profiling using NMR and MS platforms as well as statistics and bioinformatics for applications related to human health and diseases
2. Offer comprehensive and reliable end-to-end metabolomics services including, but not limited to, global profiling, targeted metabolic analysis, identification of unknown metabolites, flux analysis, and biomarker discovery and translation to a broad set of regionally located researchers and beyond
3. Provide up-to-date metabolomics training and outreach to researchers across the northwest region, as well as additional collaborators and users across the US

The primary purpose of this position is to perform mass spectrometry (MS) based research in the metabolomics field within the Northwest Metabolomics Research Center, and to ensure that standard procedures and tasks related to the workflow of the facility are correctly performed. The candidate will report to Dr. Raftery, Director of the NW-MRC, but will require limited supervision by him.

The candidate will be responsible for MS assay operations on multiple instruments, including data acquisition and analysis, will develop new assays as needed. The candidate will work with collaborators of the facility to understand their metabolomics analysis need and assist in development of analyses for their research.  The research scientist will assist with management of the facility and train and supervise multiple personnel in the successful operation of the MS instruments.

The candidate will be expected to participate and assist with grant writing activities for research initiatives as well as acquisition of new instrument purchases.

The major duties for this position fall into 2 categories:
  • Mass Spectrometry (MS) data acquisition and analysis = 70%
  • Supervision of operation of instruments; training & management of personnel on instruments = 30%

    MS data acquisition and analysis
  • Operate 1-2 Mass Spectrometers (MS)
  • Perform Assay operations; Develop new Assay operations as needed
  • Acquire data from MS operations
  • Perform data analysis including peak integration and report generation
  • Collaborate with PIs and other investigators to develop research methods
  • Prepare data for publication; draft academic papers and presentations
  • Participate in grant proposal writing activities
                                                                       
    Supervision of operation of instruments; training & management of personnel on instruments
  • Assist in managing the operations of the MS facilities
  • Supervise and train personnel involved in sample preparation and instrument operation;
  • Assist in new instrument acquisition as required
      
    Minimum Required Qualifications
    Education: BA in Chemistry, Biochemistry, Bioengineering or equivalent
    Type and Years of Experience:  3-5 years of experience in mass spectrometry analysis

    Specific knowledge, skills and abilities required to perform the job satisfactorily include:
  • Minimum 3 years of experience in targeted or global LC-MS, including assay development
  • Strong mathematical skills and experience performing calculations in Excel
  • Excellent problem solving skills especially involving chemical analysis or instrumentation
  • Ability to present detailed scientific material
  • Understands and implements good laboratory techniques

    Other Required Qualifications:
  • Excellent communication skills – both written and verbal
  • Ability to lead multiple small or larger projects that may last years and involve multiple personnel in different disciplines or with different expertise
  • Attention to detail
  • Ability to work with a variety of personnel, including research collaborators, clinical researchers, administrative staff and outside entities
  • Professional presentation of materials, self and department in all matters

    Desired Qualifications
  • M.S. or Ph.D. in Chemistry or Biochemistry, or similar field
  • Experience in statistical analysis
  • Programming experience

    Application Process:
    The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process.  These assessments may include Work Authorization, Cover Letter and/or others.  Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
  • Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.

    The University of Washington is a leader in environmental stewardship & sustainability, and committed to becoming climate neutral.

    The University of Washington is an equal opportunity, affirmative action employer. To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 / 206-543-6452 (tty) or dso@uw.edu.