SENIOR RESEARCH SCIENTIST - GENETICS
University of Washington Seattle, WA Full-time Research
Posted on May 10, 2020
|Job Location:||UW Medical Center - Montlake|
|Closing Info:||Open Until Filled|
|Salary:||Salary commensurate with education and experience.|
Our Laboratory Medicine department has an outstanding opportunity for a FULL-time (100%) Senior Research Scientist. This individual will oversee and coordinate the research development and validation on new genomic-based diagnostic testing in the Genetics Division.
The Senior Research Scientist of Technical Development is responsible for the technical and development of the research projects and experiments in Genetics, to support research in optimizing of high-complexity molecular assays, and process improvement that will be used for the Genetics Division, including liaising with the Molecular Hematopathology laboratory. This will include coordinating research efforts in laboratory automation of next-generation sequencing based assay across division laboratories.
Additionally, the person in this role will lead automation efforts in the genetics research laboratories involving liquid handlers. Develop process improvements in workflow of next generation sequencing based tests. Develop and implement clinical research validation to be used for genetic and genomic test services based on next-generation sequencing and related technologies. Facilitate and lead the research process of streamlining and harmonization of wet bench aspects of next-generation sequencing workflows across Genetics division laboratories. Plans, develops, and coordinates research and development of technical workflows and facilities of the Genetics division laboratories. Oversee the creation of technical development documentation (validation document, procedures) for new and updated Genetics division tests from research to specifications required by regulatory agencies including CAP, CLIA, FDA, and Study Sponsors and PIs. Negotiate with vendors for reagents and instrumentation needed for expanded next-generation sequencing services across the Genetics division laboratories. Review current Genetics division technical development plans and assist in planning for annual division research and development technical goals and objectives. Interact with laboratory clients (physicians and other medical providers) related to aspects of technical development. Report to faculty laboratory directors. Assist in test interpretation and test reporting from research validated tests. Review high-complexity quality control data for Genetics division laboratories. Participate as needed in teaching of undergraduates, graduate students, residents and fellows. Participate in research and scholarship related to the Genetics Division leadership
Doctorate Degree in Genetics, Molecular Cell Biology, Biochemistry, or other Life Sciences, OR Ph.D. in Genetics, Molecular Cell Biology, Biochemistry or other Life Sciences, with at least 6 years or more of genetics or molecular biology laboratory experience.
Master’s degree candidates with exceptional qualifications may be considered. Equivalent education or experience may substitute for minimum requirements.
- Experience in molecular biology methods and data analysis.
- Experience with instrumentation associated with next-generation sequencing (NGS) including Illumina sequencing instruments and automated liquid handling instruments used in NGS.
- Strong teamwork and interpersonal skills. Strong organizational and documentation skills suitable to a clinical laboratory environment.
- Extensive experience with next-generation sequencing methods and data analysis.
- Experience in clinical diagnostics. Management experience in a laboratory setting.
- Experience with next-generation sequencing and/or cell-free DNA laboratory methods.
- Understanding of the principles of cancer genetics and clinical molecular diagnostics.
- Familiarity with standard bioinformatics tools and databases.
This position provides opportunities to work in a fast-paced work environment. As an employee you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please view this page.